ALEXANDRIA, Va., June 17 -- United States Patent no. 12,310,991, issued on May 27, was assigned to Figene LLC (Houston).
"Stimulation of angiogenesis by fibroblast derived exosomes" was invented by Pete O'Heeron (Houston), Thomas Ichim (San Diego) and Kristin Comella (Weston, Fla.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are methods, means, and compositions of matter useful for the stimulation of angiogenesis directly by administration of membrane vesicles, such as fibroblast-derived exosomes, and/or through induction of angiogenic cytokines from blood cells contacted with fibroblast-derived exosomes. The invention provides means of treating conditions in which angiogenesis is beneficial thro...