ALEXANDRIA, Va., June 6 -- United States Patent no. 12,280,095, issued on April 22, was assigned to Fibrosoft Pte Ltd (Orchard, Singapore).

"Tissue modifier and uses therefor" was invented by David Chin (Auchenflower, Australia).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are compositions, methods, uses, kits and articles of manufacture, which are based on the use of a hyaluronidase and a collagen-reducing agent, for reducing or inhibiting the development of fibrosis in a tissue, or for treating collagen-mediated disorders. In specific embodiments, the collagen-mediated disorders are fibroproliferative disorders involving alterations of collagen, including fibromatoses such as Dupuytren's disease...