US Patent Issued to F. Hoffmann-La Roche on Dec. 30 for "Composition comprising recombinant GplbAlpha receptor protein" (American, Spanish Inventors)

ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,509,500, issued on Dec. 30, was assigned to F. Hoffmann-La Roche AG (Basel, Switzerland).

"Composition comprising recombinant GplbAlpha receptor protein" was invented by Elizabeth Booth (Berkeley, Calif.), Virginia Montanini (Barcelona, Spain), John A. Hall (Rohnert Park, Calif.) and Jody Berry (Easton, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Various aspects of the invention relate to recombinant polypeptides that specifically bind human von Willebrand Factor. Such recombinant polypeptides typically include a modified extracellular domain of platelet glycoprotein lbAlpha that typically comprises at least one mutation selected from G233T, D235...