ALEXANDRIA, Va., March 12 -- United States Patent no. 12,247,202, issued on March 11, was assigned to EXCLCIRC (SUZHOU) BIOMEDICAL Co. LTD. (Suzhou, China).

"Circular RNAS and preparation methods thereof" was invented by Dongsheng Dai (Suzhou, China), Lynn Shan (Suzhou, China) and Zilin Dai (Suzhou, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "DNA molecules for making a circular RNA are provided. The DNA molecule may include elements operably connected and arranged, from a 5' to 3' direction, in the following order: (a) an intron fragment that includes a full-length intron; (b) an E2 fragment which includes a downstream exon of the full-length intron; and (c) an E1 fragment which includes an upstream...