ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,398,096, issued on Aug. 26, was assigned to Evonik Operations GmbH (Essen, Germany).

"Method for preparing guanidino acetic acid" was invented by Timo Stahl (Limeshain, Germany), Axel Ronneburg (Hanau, Germany), Barbara Jager (Mainhausen, Germany) and Philipp Roth (Hanau, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for preparing guanidino acetic acid involves reacting cyanamide and glycine in an aqueous reaction mixture in the presence of a base. The ammonia content in the reaction mixture is controlled to be below 20 g/L, and the dicyandiatrade content in the reaction mixture is kept below 5 wt.-%."

The patent was filed on Aug. 19,...