ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,465,568, issued on Nov. 11, was assigned to ethris GmbH (Planegg, Germany).
"Cryoprotective agents for particulate formulations" was invented by Christian Dohmen (Munich) and Philipp Beck (Munich).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided is a composition comprising (i) a nano- or microparticle formulation of a therapeutically active agent which is suspended in a liquid phase, and (ii) at least one cryoprotective additive selected from C3-C5 alkanes substituted by one or two hydroxy groups which stabilizes the particle formulation. Further aspects relate to a solid composition which can be obtained by freezing the stabilized composition, an...