ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,441,743, issued on Oct. 14, was assigned to Etern Biopharma (Shanghai) Co. Ltd. (Shanghai).
"Spiro aromatic ring compound and use thereof" was invented by Qiangang Zheng (Shanghai), Ming Xu (Shanghai), Qinglong Zeng (Shanghai), Jing Li (Shanghai) and Hao Zhuge (Shanghai).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided is a compound of formula I or a pharmaceutically acceptable salt, enantiomer, diastereomer, tautomer, solvate, isotopic substituent, polymorph, prodrug, or metabolite thereof. Also provided is a method for preparing the compound of formula I. The compound of formula I has higher inhibitory activity against SHP2, and thus can be used...