ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,458,649, issued on Nov. 4, was assigned to ESTETRA SRL (Liege, Belgium).
"Contraceptive compositions with reduced adverse effects" was invented by Jean-Michel Foidart (Liege, Belgium).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a combined oral contraceptive with a reduced risk for side effects, including a reduced risk for QT interval prolongation, a reduced risk for testosterone decrease and a reduced risk for elevated C-reactive protein levels when compared to other combined oral contraceptives. The estetrol/drospirenone combined oral contraceptive described herein shows favorable pharmacokinetics for the progestogeni...