ALEXANDRIA, Va., June 6 -- United States Patent no. 12,280,123, issued on April 22, was assigned to EPICENTRX INC. (La Jolla, Calif.).
"Recombinant adenoviruses carrying transgenes" was invented by Christopher Larson (San Diego), Bryan Oronsky (Los Altos Hills, Calif.) and Tony R. Reid (San Diego).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are recombinant adenoviruses with one or more nucleotide sequences inserted between two viral transcription units, formulations comprising the recombinant adenoviruses, and methods of treatment using the recombinant adenoviruses. In some embodiments, the one or more nucleotide sequences are inserted in an IX-E2 insertion site and/or an L5-E4 insertion s...