US Patent Issued to ENTERPRISE THERAPEUTICS on July 29 for "Substituted benzodiazoliums as ENaC inhibitors" (British Inventors)

ALEXANDRIA, Va., July 30 -- United States Patent no. 12,371,436, issued on July 29, was assigned to ENTERPRISE THERAPEUTICS Ltd. (Falmer, Great Britain).

"Substituted benzodiazoliums as ENaC inhibitors" was invented by Clive McCarthy (Abingdon, Great Britain), Jonathan David Hargrave (Abingdon, Great Britain), Duncan Alexander Hay (Abingdon, Great Britain), Thomas Beauregard Schofield (Abingdon, Great Britain) and Naomi Went (Abingdon, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compounds of general formula (I) wherein R1, R2, R3, R4, R5 and X are as defined herein are inhibitors of the epithelial sodium channel (ENaC) and are useful for the treatment or prevention respiratory diseases and c...