US Patent Issued to Entasis Therapeutics on Aug. 26 for "Managing microbial dysbiosis with temocillin" (Massachusetts Inventors)

ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,396,984, issued on Aug. 26, was assigned to Entasis Therapeutics Inc. (Waltham, Mass.).

"Managing microbial dysbiosis with temocillin" was invented by Ramkumar Iyer (Arlington, Mass.), Adam Shapiro (Wellesley, Mass.) and Samir Moussa (Framingham, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods of using temocillin to control microbial dysbiosis arising from, in certain instances, enterobacteriacea overgrowth such as overgrowth from adherent invasive E. coli (AIEC). Methods of using temocillin to treat intestinal disorders and symptoms of such caused by microbial dysbiosis, as well as other disorders are contemplated herei...