US Patent Issued to Ensysce Biosciences on Aug. 12 for "Enzyme-cleavable methadone prodrugs and methods of use thereof" (California Inventor)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,384,744, issued on Aug. 12, was assigned to Ensysce Biosciences Inc. (La Jolla, Calif.).

"Enzyme-cleavable methadone prodrugs and methods of use thereof" was invented by Lynn Kirkpatrick (La Jolla, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides methadone prodrugs, pharmaceutical compositions, and their methods of use, where the pharmaceutical compositions comprise a methadone prodrug that provides enzymatically-controlled release of methadone, and an optional enzyme inhibitor that interacts with the enzyme(s) that mediates the enzymatically-controlled release of methadone from the prodrug so as to attenuate enzymat...