ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,508,224, issued on Dec. 30, was assigned to EndoProtech Inc. (Louisville, Ky.).

"Treating microvascular dysfunction" was invented by Claudio Maldonado (Louisville, Ky.) and Phillip Bauer (Louisville, Ky.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to compositions comprising phospholipids, lipid vesicles, and/or liposomes, and methods of use thereof. In one aspect, the present disclosure relates to methods and compositions for delivery of, biologically active lipids to reduce microvascular dysfunction and infarct size during revascularization of the blocked artery in a mammalian subject."

The patent was filed on Jan. 24...