ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,441,761, issued on Oct. 14, was assigned to Encodia Inc. (San Diego).
"Conjugation reagents and methods using 1,2-cyclohexanediones" was invented by Robert C. James (San Diego), Stephen Verespy III (San Diego), Eric Cunyu Zhou (San Diego), Eric Okerberg (San Diego), Kelsey Rose Schramma (San Diego) and Fei Huang (San Diego).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to methods to use cyclohexan-1,2-dione (CHD) groups to attach labels, linkers, and other molecules to a target compound comprising a CHD-reactive group such as a guanidine, amidine, urea, thiourea and the like. Methods of the invention include milder conditio...