US Patent Issued to Enanta Pharmaceuticals on April 22 for "Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., June 6 -- United States Patent no. 12,281,140, issued on April 22, was assigned to Enanta Pharmaceuticals Inc. (Watertown, Mass.).

"Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof" was invented by Guoqiang Wang (Belmont, Mass.), Yat Sun Or (Waltham, Mass.), Ruichao Shen (Belmont, Mass.), Jiang Long (Wayland, Mass.), Peng Dai (Auburndale, Mass.), Xuechao Xing (Wilmington, Mass.) and Jing He (Somerville, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides compounds of Formula I,pharmaceutical compositions comprising these compounds and methods of using these compounds to prevent or treat FXR-mediated or TGR5-mediated diseases or conditions....