US Patent Issued to Empirico on March 25 for "GalNAc compositions for improving siRNA bioavailability" (Wisconsin, California Inventors)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,564, issued on March 25, was assigned to Empirico Inc. (San Diego).

"GalNAc compositions for improving siRNA bioavailability" was invented by Darren H. Wakefield (Fitchburg, Wis.), David Rozema (Cross Plains, Wis.) and Omri Gottesman (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein, are compositions comprising GalNAc moieties that may be conjugated to an oligonucleotide. The oligonucleotide may be a small interfering RNA or an antisense oligonucleotide. Also provided herein are methods of treatment that include administering the composition to a subject."

The patent was filed on Oct. 9, 2023, under Application No. 18/378,0...