ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,458,603, issued on Nov. 4, was assigned to Emory University (Atlanta).
"Fusion proteins having a toxin and cancer marker, nanoparticles, and uses related thereto" was invented by Lily Yang (Atlanta), Xiangxue Guo (Atlanta), Hui Mao (Johns Creek, Ga.) and Wei Chen (Atlanta).
According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure relates to nanoparticles coated with fusion proteins comprising a domain that binds a cancer marker and a domain comprising a toxic polypeptide. In certain embodiments, the targeted cancer marker is urokinase plasminogen activator receptor (uPAR) insulin-like growth factor 1 receptor (IGF1R), EGFR, HER2, and/or other member ...