US Patent Issued to EmendoBio on March 25 for "Method to inactivate a mutant allele of an ELANE gene" (Israeli Inventors)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,599, issued on March 25, was assigned to EmendoBio Inc. (Wilmington, Del.).

"Method to inactivate a mutant allele of an ELANE gene" was invented by David Baram (Tel Aviv, Israel), Lior Izhar (Tel Aviv, Israel), Asael Herman (Ness-Ziona, Israel), Rafi Emmanuel (Ramla, Israel), Liat Rockah (Rishon LeZion, Israel), Nadav Marbach-Bar (Rehovot, Israel), Michal Golan Mashiach (Ness-Ziona, Israel) and Joseph Georgeson (Rehovot, Israel).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods for inactivating in a cell a mutant allele of the elastase, neutrophil expressed gene (ELANE gene) gene having a mutation associated with severe congenital neutropenia (...