ALEXANDRIA, Va., June 5 -- United States Patent no. 12,274,758, issued on April 15, was assigned to EmendoBio Inc. (Wilmington, Del.).

"Guide RNA that targets a mutant human inosine monophosphate deyhydrogenase I allele" was invented by Lior Izhar (Tel Aviv, Israel), David Baram (Nir Zvi, Israel), Joe Georgeson (Rehevot, Israel), Michal Golan-Mashiach (Ness-Ziona, Israel), Asael Herman (Ness-Ziona, Israel) and Rafi Emmanuel (Ramla, Israel).

According to the abstract* released by the U.S. Patent & Trademark Office: "RNA molecules comprising a guide sequence portion having 17-20 nucleotides in the sequence of 17-20 contiguous nucleotides set forth in any one of SEQ ID NOs: 1-3010 and compositions, methods, and uses thereof."

The patent was...