ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,440,493, issued on Oct. 14, was assigned to Eli Lilly and Co. (Indianapolis).

"Combination therapy for treating cancer comprising substituted piperazines" was invented by Nathan Arthur Brooks (Fishers, Ind.) and Raymond Gilmour (Indianapolis).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to combination therapy with (a) a mutant IDH inhibitor having the Formula I and (b) one or more of an antimetabolite agent, a hypomethylating agent, and a mutant Flt3 (Flt3) inhibitor, for the treatment of cancer."

The patent was filed on March 22, 2021, under Application No. 17/912,383.

*For further information, including images, charts ...