ALEXANDRIA, Va., July 16 -- United States Patent no. 12,358,965, issued on July 15, was assigned to ELI LILLY AND COMPANY (Indianapolis).

"Relaxin analogs and methods of using the same" was invented by Petra Verdino (San Diego), Stacey Lynn Lee (San Diego) and Xiaojun Wang (Carmel, Ind.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Relaxin (RLN) analogs are disclosed including modifications that increase half-life when compared to native, human RLN, that maintain selectivity to the RXFP1 receptor and that provide in vitro and in vivo stability for improved druggability properties and less immunogenicity. Pharmaceutical compositions also are disclosed that include one or more of the RLN analogs described her...