ALEXANDRIA, Va., Dec. 23 -- United States Patent no. 12,503,442, issued on Dec. 23, was assigned to ELI LILLY AND COMPANY (Indianapolis).

"Phenyl-3,4-dihydroisoquinolin-2(1h)-yl-ethan-1-one derivatives as dopamine d1receptor positive allosteric modulators" was invented by Junliang Hao (Indianapolis), Richard D. Johnston (Indianapolis), Gregory Lawrence Lackner (Indianapolis), Erik J. Hembre (Indianapolis) and Kjell A. Svensson (Indianapolis).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides certain (phenyl)-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one related compounds of formula I as D1 positive allosteric modulators (PAMs), and pharmaceutical compositions thereof. The invention further pr...