ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,356, issued on June 17, was assigned to ELEMENT BIOSCIENCES INC. (San Diego).

"Multipart reagents having increased avidity for polymerase binding" was invented by Sinan Arslan (San Diego), Chunhong Zhou (San Diego), Molly Min He (San Diego), Matthew Kellinger (San Diego), Hui Zhen Mah (San Diego), Michael Previte (San Diego) and Lei Sun (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Multivalent binding compositions including a particle-nucleotide conjugate having a plurality of copies of a nucleotide attached to the particle are described. The multivalent binding compositions allow one to localize detectable signals to active regions of b...