ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,458,815, issued on Nov. 4, was assigned to Elekta Instrument AB (Stockholm).
"Dose volume histogram optimization based on quantile regression" was invented by Jens Olof Sjolund (Uppsala, Sweden) and Carl Axel Hakan Nordstrom (Sollentuna, Sweden).
According to the abstract* released by the U.S. Patent & Trademark Office: "Dose-volume criteria may be equivalently expressed in terms of quantiles. This re-formulation of a dose-volume criteria allows incorporation of dose-volume criteria into a full optimization problem. Radiotherapy treatment techniques are described that may apply optimization-based formulation of quantiles to express dose-volume criterion as an inequality involving an o...