US Patent Issued to Eisai R&D Management on Sept. 23 for "Method for synthesis of diazabicyclo[6.2.0decane related compounds" (Massachusetts Inventors)

ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,421,246, issued on Sept. 23, was assigned to Eisai R&D Management Co. Ltd. (Tokyo).

"Method for synthesis of diazabicyclo[6.2.0decane related compounds" was invented by Francis G. Fang (Andover, Mass.), Branko Mitasev (North Reading, Mass.) and Jiong Yang (Andover, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for the synthesis of diazabicyclo[6.2.0]decane compounds is provided. The synthesis proceeds by stereoselective synthesis of a chiral lactone followed by azetidine formation via a series of chemoselective reactions. Bicyclization results with the formation of diazobicyclo[6.2.0]decane related compounds."

The patent was filed on J...