ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,384,824, issued on Aug. 12, was assigned to Eisai R&D Management Co. Ltd. (Tokyo).
"Method for producing an active hepatocyte growth factor (HGF)" was invented by Masashi Shimizu (Tsukuba, Japan), Toshitaka Sato (Kobe, Japan) and Yoshihisa Arita (Kobe, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a method for producing active hepatocyte growth factor activator (HGFA) and active hepatocyte growth factor (HGF) without using animal serum. The present invention relates to a method for producing active HGFA without using animal serum. The method is characterized in that it comprises a step of obtaining a culture superna...