ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,478,687, issued on Nov. 25, was assigned to Dyne Therapeutics Inc. (Waltham, Mass.).
"United states" was invented by Romesh R. Subramanian (Framingham, Mass.), Mohammed T. Qatanani (Waltham, Mass.) and Timothy Weeden (Waltham, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the disclosure relate to complexes comprising a muscle-targeting agent covalently linked to a molecular payload. In some embodiments, the muscle-targeting agent specifically binds to an internalizing cell surface receptor on muscle cells. In some embodiments, the molecular payload promotes the expression or activity of a functional dystrophin protein. In some embodime...