ALEXANDRIA, Va., June 6 -- United States Patent no. 12,280,122, issued on April 22, was assigned to Dyne Therapeutics Inc. (Waltham, Mass.).
"Muscle targeting complexes and uses thereof for treating myotonic dystrophy" was invented by Romesh R. Subramanian (Framingham, Mass.), Mohammed T. Qatanani (Waltham, Mass.), Timothy Weeden (Waltham, Mass.) and Cody A. Desjardins (Waltham, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the disclosure relate to complexes comprising a muscle-targeting agent covalently linked to a molecular payload. In some embodiments, the muscle-targeting agent specifically binds to an internalizing cell surface receptor on muscle cells. In some embodiments, the molecul...