US Patent Issued to DYNAVAX TECHNOLOGIES on Aug. 5 for "Toll-like receptor antagonist compounds and methods of use" (California Inventors)

ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,255, issued on Aug. 5, was assigned to DYNAVAX TECHNOLOGIES Corp. (Emeryville, Calif.).

"Toll-like receptor antagonist compounds and methods of use" was invented by Albert Frederick Candia III (San Mateo, Calif.), Richard Thomas Beresis (San Francisco) and Robert L. Coffman (Portola Valley, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to compounds of formula (I):or a salt or solvate thereof, wherein the variables are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are antagonists of toll-like receptors such as TLR7, TLR8 and/or TLR9 that are useful for inhibiting immune response and...