ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,419,946, issued on Sept. 23, was assigned to Duke University (Durham, N.C.).
"Stabilized 9 and 10 segmented influenza viruses as a vaccine platform and methods of making and using same" was invented by Nicholas S. Heaton (Durham, N.C.), Alfred Harding (Durham, N.C.), Griffin Haas (New York) and Alanson Girton (Frederick, Md.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a modified influenza A virus (IAV) comprising, consisting of, or consisting essentially of at least one artificial gene segment comprising a duplicated packaging signal, the result of which is a modified IAV that is replication competent and avirulent, an...