US Patent Issued to Duke University on June 10 for "Gene editing using homology-independent universal genome engineering technology" (North Carolina Inventors)

ALEXANDRIA, Va., June 18 -- United States Patent no. 12,325,855, issued on June 10, was assigned to Duke University (Durham, N.C.).

"Gene editing using homology-independent universal genome engineering technology" was invented by Yudong Gao (Durham, N.C.) and Scott Soderling (Durham, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are the genetic constructs for a Homology-Independent Universal Genome Editing (HiUGE) system and methods of using said HiUGE system for genome editing. The invention relates to compositions comprising gRNA polynucleotides, insert polynucleotides, and a CRISPR-based nuclease or polynucleotide encoding a CRISPR-based nuclease."

The patent was filed on Feb. 15, ...