ALEXANDRIA, Va., June 18 -- United States Patent no. 12,325,855, issued on June 10, was assigned to Duke University (Durham, N.C.).
"Gene editing using homology-independent universal genome engineering technology" was invented by Yudong Gao (Durham, N.C.) and Scott Soderling (Durham, N.C.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are the genetic constructs for a Homology-Independent Universal Genome Editing (HiUGE) system and methods of using said HiUGE system for genome editing. The invention relates to compositions comprising gRNA polynucleotides, insert polynucleotides, and a CRISPR-based nuclease or polynucleotide encoding a CRISPR-based nuclease."
The patent was filed on Feb. 15, ...