US Patent Issued to Duke University on Jan. 27 for "Small molecule inhibitors of voltage-gated sodium channel 1.7 and methods of using same" (North Carolina Inventors)

ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,533,341, issued on Jan. 27, was assigned to Duke University (Durham, N.C.).

"Small molecule inhibitors of voltage-gated sodium channel 1.7 and methods of using same" was invented by Andrey Bortsov (Durham, N.C.), Sharat Chandra (Durham, N.C.) and Ru-Rong Ji (Durham, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods for treating conditions including itch and pain are described. The methods include administering a therapeutically effective amount of an N-substituted indole Nav1.7 inhibitor to a subject in need thereof. New N-substituted indole compounds, useful as Nav1.7 inhibitors for the treatment of itch and/or pain are also provided, as well...