US Patent Issued to Duke University on Aug. 5 for "Compositions comprising hyperpolarized probes for H 2 O 2 sensing and methods of using same" (North Carolina Inventors)

ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,377,173, issued on Aug. 5, was assigned to Duke University (Durham, N.C.).

"Compositions comprising hyperpolarized probes for H 2 O 2 sensing and methods of using same" was invented by Qiu Wang (Durham, N.C.) and Hyejin Park (Durham, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are molecular probes for hyperpolarized 15N magnetic resonance spectroscopic imaging (MRSI) and their use for detecting reactive species (e.g., hydrogen peroxide) and imaging of oxidative stress. In particular, 15N-boronobenzyl-4-cyanopyridinium (15N-BBCP) demonstrated highly favorable physicochemical and hyperpolarization properties, including long spin-lattice re...