ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,581, issued on Aug. 5, was assigned to Duke University (Durham, N.C.).

"Compositions and methods for metabolic control of a biofermentation process with synthetic metabolic valves" was invented by Michael David Lynch (Durham, N.C.) and Zhixia Ye (Raleigh, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides compositions and methods for rapid production of chemicals in genetically engineered microorganisms in a large scale. Also provided herein is a high-throughput metabolic engineering platform enabling the rapid optimization of microbial production strains. The platform, which bridges a gap between current in vivo and ...