ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,398,425, issued on Aug. 26, was assigned to DUKE UNIVERSITY (Durham, N.C.).
"Antidote-mediated reversal of extracellular aptamer staining" was invented by Bruce Sullenger (Durham, N.C.), Bethany Gray (Durham, N.C.) and Michael Nichols (Durham, N.C.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are compositions and methods for sorting and/or identifying live cells. The compositions and methods provide for staining of live cells with aptamer so particular cells can be identified within or sorted from a heterogeneous population of live cells and subsequent reversal of the staining to prepare sorted and/or identified cells in their native s...