ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,385,005, issued on Aug. 12, was assigned to Duke University (Durham, N.C.).

"Compositions and methods for improved malonyl-CoA biosynthesis using 2-stage dynamic metabolic control" was invented by Michael Lynch (Durham, N.C.) and Jeovanna Rios (Durham, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods and microorganisms for improved malonyl-CoA flux and production of products having malonyl-CoA as a precursor. The methods comprise dynamically regulating, in a stationary phase of a method, a nitrogen regulatory protein. The methods may dynamically regulate more than one gene."

The patent was filed on March 21, 2023, under Application No. 18/18...