US Patent Issued to Duke University, North Carolina State University on Dec. 30 for "Genome engineering with CRISPR-Cas systems in eukaryotes" (North Carolina Inventors)

ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,509,492, issued on Dec. 30, was assigned to Duke University (Durham, N.C.) and North Carolina State University (Raleigh, N.C.).

"Genome engineering with CRISPR-Cas systems in eukaryotes" was invented by Charles A. Gersbach (Durham, N.C.), Adrian Pickar Oliver (Rougemont, N.C.) and Rodolphe Barrangou (Raleigh, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are Type I Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas) programmable systems and methods of using said Type I CRISPR/Cas programmable systems for activating gene expression, repressing gene expression, and gene editing. The disclosure ...