US Patent Issued to Duke University, Baylor College of Medicine on Nov. 11 for "3' UTR CRISPR-DCAS 13 engineering system and methods of using same" (North Carolina, California Inventors)

ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,467,043, issued on Nov. 11, was assigned to Duke University (Durham, N.C.) and Baylor College of Medicine (Houston).

"3' UTR CRISPR-DCAS 13 engineering system and methods of using same" was invented by Qianben Wang (Durham, N.C.), Fuwen Yuan (Durham, N.C.) and Wei Li (Irvine, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a 3'UTR CRISPR-dCas13 Engineering System, and methods of using said system, that allows for the manipulation of the length of 3' untranslated regions by using gRNAs to guide catalytically dead Cas13 to sites upstream and/or downstream of the desired poly adenylation sites. One aspect of the disclo...