ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,496,384, issued on Dec. 16, was assigned to DSRCo BV (Ghent, Belgium).

"Formulations and methods for direct sodium removal in patients having heart failure and/or severe renal dysfunction" was invented by Jeffrey Testani (Guilford, Conn.), Christopher McIntyre (Ontario, Canada), Ian Crosbie (London) and Oliver Goedje (Strasslach, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "A direct sodium removal ("DSR") infusate regimen and methods of use are provided for removing sodium and reducing fluid overload in patients with severe renal dysfunction and/or heart failure, in which a patient has at least a first DSR session with a first DSR infusate hav...