ALEXANDRIA, Va., July 30 -- United States Patent no. 12,371,680, issued on July 29, was assigned to DNA Script SAS (Le Kremlin-Bicetre, France).

"Terminal deoxynucleotidyl transferase variants and uses thereof" was invented by Elise Champion (Paris), Jerome Loc'h (Le Kremlin-Bicetre, France), Mikhael Soskine (Franconville, France) and Elodie Sune (Le Kremlin-Bicetre, France).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is directed to terminal deoxynucleotidyltransferase (TdT) variants that (i) comprise an amino acid sequence that is at least a specified percent identical to an indicated SEQ ID NOs and have at least one substitution at Q455 or at least Q455 plus at least one further sub...