US Patent Issued to DISHMAN CARBOGEN AMCIS on Oct. 14 for "Process for the preparation of methylene blue" (Indian Inventors)

ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,441,694, issued on Oct. 14, was assigned to DISHMAN CARBOGEN AMCIS LTD. (Ahmedabad, India).

"Process for the preparation of methylene blue" was invented by Janmejay Rajnikant Vyas (Ahmedabad, India), Himani Dhotre (Ahmedabad, India), Denish H. Shah (Ahmedabad, India) and Krunal Parikh (Ahmedabad, India).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein is a process for preparation of 3,7-bis-(dimethy-lamino)-phenothiazin-5-ium chloride: Formula (I). The said process comprises preparing 3,7-dibromophenothiazin-5-iumbromide wet Crude(III) from phenothiazine (II) alongpro-moter, catalyst and brominating agent in presence of organic solvent; pre...