ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,523,631, issued on Jan. 13, was assigned to DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (Singapore).

"Genome integrity analysis of adeno-associated virus vectors" was invented by Handy Yowanto (Walnut, Calif.), Elliot B. Jones (Redwood City, Calif.) and Jane Luo (Brea, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A CE based method and kit for the determination of the size and purity of an AAV genome which relies on Capillary Electrophoresis-Laser Induced Fluorescence (CE-LIF) analysis. These methods and kits are capable of detecting intact and partial genomes in a virus vectors such as adeno-associated viruses as well as remove small size impurities....