ALEXANDRIA, Va., March 19 -- United States Patent no. 12,252,471, issued on March 18, was assigned to DERMAVANT SCIENCES GMBH (Basel, Switzerland).

"Isoquinoline compounds and their use in treating AhR imbalance" was invented by Channa K. Jayawickreme (Morrisville, N.C.), Susan H. Smith (Pennsburg, Pa.), Cunyu Zhang (Devon, Pa.) and William Zuercher (Mies, Switzerland).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is directed to novel compounds of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof. Pharmaceutical compositions comprising a compound of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof, are also described. The invent...