US Patent Issued to DEPIXUS on May 20 for "Optimization of in vitro isolation of nucleic acids using site-specific nucleases" (French Inventors)

ALEXANDRIA, Va., June 16 -- United States Patent no. 12,305,218, issued on May 20, was assigned to DEPIXUS (Paris).

"Optimization of in vitro isolation of nucleic acids using site-specific nucleases" was invented by Jimmy Ouellet (Lardy, France) and Jerome Maluenda (Saint Michel S/orge, France).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a method of preparing a nucleic acid molecule comprising a target region for isolation from a sample, said method comprising the steps of contacting a population of nucleic acid molecules with a first Class 2 Type V Cas protein-gRNA complex, wherein the gRNA comprises a guide segment that is complementary to a first sequence within a nuclei...