US Patent Issued to DENALI THERAPEUTICS on Dec. 16 for "Process for the preparation of pyrimidinyl-4-aminopyrazole compounds" (California Inventors)

ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,387, issued on Dec. 16, was assigned to DENALI THERAPEUTICS INC. (South San Francisco, Calif.).

"Process for the preparation of pyrimidinyl-4-aminopyrazole compounds" was invented by Travis Remarchuk (South San Francisco, Calif.) and Anantha Sudhakar (South San Francisco, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to methods of making LRRK2-inhibiting, pyrimidinyl-4-aminopyrazole compounds and intermediates of formulae I and IV: The compounds are useful as LRRK2 inhibitors in the treatment of LRRK2 mediated diseases, and as intermediates for their manufacture."

The patent was filed on Oct. 26, 2023, under A...