ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,460,185, issued on Nov. 4, was assigned to Demetrix Inc. (Berkeley, Calif.).
"Optimized cannabinoid synthase polypeptides" was invented by Andrew Horwitz (Oakland, Calif.), Jeff Wong (Berkeley, Calif.), Darren Platt (San Francisco) and Jeff Ubersax (San Francisco).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides engineered variants of a cannabidiolic acid synthase (CBDAS) polypeptide comprising an amino acid sequence of SEQ ID NO:3 with one or more amino acid substitutions, nucleic acids comprising nucleotide sequences encoding said engineered variants, methods of making modified host cells comprising said nucleic acids, modi...