US Patent Issued to David Bermudes on Aug. 5 for "Chimeric protein toxins for expression by therapeutic bacteria" (California Inventors)

ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,536, issued on Aug. 5, was assigned to David Bermudes (Woodland Hills, Calif.).

"Chimeric protein toxins for expression by therapeutic bacteria" was invented by David Gordon Bermudes (Woodland Hils, Calif.) and David Quintero (Northridge, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Bacteria with tumor-targeting capability express, surface displayed, secreted and/or released modified chimeric therapeutic proteins with enhanced therapeutic activity against a neoplastic tissue including solid tumors, lymphomas and leukemias. The bacteria may be attenuated, non-pathogenic, low pathogenic or a probiotic. The chimeric proteins may be protease sen...