ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,592, issued on Dec. 16, was assigned to Danmarks Tekniske Universitet (Ks. Lyngby, Denmark).
"Scaffolds with stabilized MHC molecules for immune-cell manipulation" was invented by Sine Reker Hadrup (Virum, Denmark), Soren Nyboe Jakobsen (Charlottenlund, Denmark) and Sunil Kumar Saini (Bagsvaerd, Denmark).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to artificial antigen presenting cell (aAPC) scaffolds to provide cells with specific functional stimulation to obtain phenotypic and functional properties ideal to mediate tumor regression or viral clearance. In particular, the scaffolds of the present invention comprise st...