ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,460,191, issued on Nov. 4, was assigned to Danisco US Inc. (Palo Alto, Calif.).
"Cas9 variants and methods of use" was invented by Ryan L Frisch (Newark, Del.) and Hongxian He (Wilmington, Del.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods are provided for variant Cas systems and elements comprising such systems, including, but not limiting to, Cas endonuclease variants, guide polynucleotide/Cas endonuclease complexes comprising Cas endonuclease variants, as well as guide polynucleotides and guide RNA elements that can interact with Cas endonuclease variants. Compositions and methods are provided for genome modification of a tar...