US Patent Issued to DANA-FARBER CANCER INSTITUTE on Oct. 14 for "Compositions and methods using an epigenetic inhibitor" (Massachusetts Inventors)

ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,440,451, issued on Oct. 14, was assigned to DANA-FARBER CANCER INSTITUTE INC. (Boston).

"Compositions and methods using an epigenetic inhibitor" was invented by Kai Wucherpfennig (Brookline, Mass.) and Rong En Tay (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are novel methods for increasing T cell effector function in a T cell populations, as well as methods for increasing T cell effector function in a subject. The methods include contacting a T cell in a T cell population with a pharmaceutical composition comprising an antagonist of histone deacetylase 3 (HD) AC3). Also provided herein are methods for identifying a compound th...